- Title
- Does milk cause constipation? A crossover dietary trial
- Creator
- Crowley, Elesa T.; Williams, Lauren T.; Roberts, Tim K.; Dunstan, Richard H.; Jones, Peter D.
- Relation
- Nutrients Vol. 5, Issue 1, p. 253-266
- Publisher Link
- http://dx.doi.org/10.3390/nu5010253
- Publisher
- MDPI AG
- Resource Type
- journal article
- Date
- 2013
- Description
- The aims of this study were to: (1) determine whether replacement of cow’s milk protein with soy resolves Chronic Functional Constipation (CFC); and (2) investigate the effects of cow’s milk β casein A1 and cow’s milk β casein A2 on CFC. Children diagnosed with CFC were recruited to one of two crossover trials: Trial 1 compared the effects of cow’s milk and soy milk; Trial 2 compared the effects of cow’s milk β casein A1 and cow’s milk β casein A2. Resolution of constipation was defined as greater than eight bowel motions during a two week intervention. Thirteen children (18 to 144 months) participated in Trial 1 (6 boys, 7 girls). Nine participants who completed the soy epoch all experienced resolution (p < 0.05). Thirty-nine children (21 to 144 months) participated in Trial 2 (25 boys, 14 girls). Resolution of constipation was highest during the washout epoch, 81%; followed by cow’s milk β casein A2, 79%; and cow’s milk β casein A1, 57%; however, the proportions did not differ statistically. The results of Trial 1 demonstrate an association between CFC and cow’s milk consumption but Trial 2 failed to show an effect from type of casein. Some other component in cow’s milk common to both A1 and A2 milk may be causing a problem in these susceptible children.
- Subject
- constipation; child; hypersensitivity; soy; casein
- Identifier
- http://hdl.handle.net/1959.13/1053052
- Identifier
- uon:15511
- Identifier
- ISSN:2072-6643
- Language
- eng
- Full Text
- Reviewed
- Hits: 4403
- Visitors: 4701
- Downloads: 360
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT01 | Publisher version (open access) | 708 KB | Adobe Acrobat PDF | View Details Download |